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  1. Salvage, S.C., K.H. Chandrasekharan, K. Jeevaratnam, A.F. Dulhunty, A.J. Thompson, A.P. Jackson and C.L-H Huang. 2017. Multiple targets for flecainide action: implications for cardiac arrhythmogenesis. Br J Pharmacol. In Press.
  2. Ruepp, M-D., H. Wei, M. Leuenberger, M. Lochner and A.J. Thompson. 2017. The Binding Orientations of Structurally-Related Ligands Can Differ; A Cautionary Note. Neuropharmacology. 119; 48-61.
  3. Thompson, A.J., S. Metzger, M. Lochner and M-D Ruepp. 2017. The Binding Orientation of Epibatidine at α7 nACh Receptors. Neuropharmacology. 116; 421-428.
  4. Lochner, M.L. and A.J. Thompson. 2016. The Muscarinic Antagonists Scopolamine and Atropine are Competitive Antagonists at 5-HT3 Receptors. Neuropharmacology. 108; 220-228.
  5. Mu, L., A.M. Herde, P.M. Ruefli, F. Sladojevich, S.M. Sephton, S.D. Kramer, A.J. Thompson, R. Schibli, S.M. Ametamey and M. Lochner. 2016. Synthesis and Pharmacological Evaluation of [11C]granisetron and [18F]fluoropalonosetron as PET Probes for 5-HT3 Receptor Imaging ACS Chem Neurosci. 7; 1552-1564.
  6. Jarvis, G.E., R. Barbosa and A.J. Thompson. 2016. Non-Competitive Inhibition of 5-HT3 Receptors by Citral, Linalool and Eucalyptol Revealed by Non-Linear Mixed Effects Modelling. JPET. 356; 549-562.
  7. Hardege, I., S. Xu, A.J. Thompson, N. Figg, R.D. Murrell-Lagnado and K.M. O'Shaughnessy. 2015. Novel insertion mutation in KCNJ5 channel produces constitutive aldosterone release from H295R cells. Mol Endocrinology. 10; 1522-1530.
  8. Ruepp, M-D., J.A. Brozik, I.J.P de Esch, R.W. Farndale, R.D. Murrell-Lagnado and A.J. Thompson. 2015. A Fluorescent Approach for Identifying P2X1 Ligands. 2015. Neuropharmacology. 98; 13-21.
  9. Barden, A.O., A.S. Goler, S.C. Humphreys, S. Tabatabaei, M. Lochner, M-D. Ruepp, T. Jack, A.J. Thompson, J.P. Jones and J.A. Brozik. 2015. Tracking Individual Membrane Proteins and Their Biochemistry: The Power of Direct Observation. 2015. Neuropharmacology. 98; 22-30.
  10. Thompson, A.J., J. Corradi, I. McGonigle, K.L. Price, C. Bouzat and S.C.R. Lummis. 2015. 5-HT3 Receptor Brain-type B-Subunits are differentially expressed in heterologous systems. ACS Chem Neurosci. 6; 1158-1164.
  11. Lochner, M. and A.J. Thompson. 2015. A Review of Fluorescent Ligands for Studying 5-HT3 Receptors. Neuropharmacology. 98; 31-40.
  12. Thompson, A.J., T. Jack, J. Simonin, M-D. Ruepp, J. Gertsch and M. Lochner. 2015. Characterizing New Fluorescent Tools for Studying 5-HT3 Receptor Pharmacology. Neuropharmacology. 90; 63-73.
  13. Lochner, M.L. and A.J. Thompson. 2014. The Antimalarial Drug Proguanil is an Antagonist at 5-HT3 Receptors. JPET. 351; 674-684.
  14. Ulens, C., R. Spurny, A.J. Thompson, M. Alqazzaz, S. Debaveye, L. Han, K. Price, J.M. Villalgordo, G. Tresadern, J.W. Lynch, S.C. Lummis. 2014. The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine. Structure. 22; 1399-1407.
  15. Thompson, A.J., M. Alqazzaz, K.L. Price, D.A. Weston, S.C.R. Lummis. 2014. Phenylalanine in the pore of ELIC modulates picrotoxinin potency but not receptor function. Biochemistry 53; 6183-6188.
  16. Thompson, A.J., M.H.P Verheij, J. Verbeek, A. Windhorst, I.J.P de Esch, S.C.R. Lummis. 2014. The binding characteristics and orientation of a novel radioligand with distinct properties at 5-HT3A and 5-HT3AB receptors Neuropharmacology. 86; 378-388.
  17. Jack, T., M-D. Ruepp, A.J. Thompson, O. Muhlemann, M. Lochner. 2014. Synthesis and characterisation of photoaffinity probes that target the 5-HT3 receptor. Chimia. 68; 239-242.
  18. Del Cadia, M., De Rienzo, F, Weston, D.A., Thompson A.J., Menziani, C and S.C.R. Lummis. 2013. Exploring a potential palonosetron allosteric binding site in the 5-HT3 receptor. BMC Biology. 21; 7523-7528.
  19. Jarvis, G.E. and A.J.Thompson. 2013. A Golden Approach to Ion Channel Inhibition. TiPS. 34; 481-488.
  20. Thompson, A.J. and S.C.R. Lummis. 2013. A Single Channel Mutation Alters Agonist Efficacy at 5-HT3A and 5-HT3AB Receptors. Br J Pharmacol. 170: 391-402.
  21. Thompson, A.J. and S.C.R. Lummis. 2013. Agonists and antagonists induce different palonosetron dissociation rates in 5-HT3A and 5-HT3AB receptors Neuropharmacology. 73: 241-246.
  22. Thompson, A.J., M.H.P. Verheij, J.E. van Muijlwijk-Koezen, S.C.R. Lummis, R. Leurs, I.J.P. de Esch. 2013. Structure-Activity Relationships of Quinoxaline-Based 5-HT3A and 5-HT3AB Receptor-Selective Ligands. ChemMedChem. 8: 946-955.
  23. Thompson, A.J. and S.C.R. Lummis. 2013. Discriminating between 5-HT3A and 5-HT3AB receptors. Br J Pharmacol. 169; 736-747.
  24. Thompson, A.J. 2013. Recent Developments in 5-HT3 Receptor Pharmacology. TiPS. 34; 100-109.
  25. Kesters, D., A.J. Thompson, M. Brams, R. van Elk, R. Spurny, M. Geitmann, J.M. Villalgordo, A. Guskov, H.U. Danielson, S.C.R. Lummis, A.B. Smit, C. Ulens. 2013. Structural basis of ligand recognition in 5-HT3 receptors. EMBO Reports. 14: 49-56.
  26. Thompson, A.J., M.H.P. Verheij, J. van Muijlwijk-Koezen, S.C.R. Lummis, R. Leurs, I.J.P. de Esch. 2012. Design, synthesis and structure-activity relationships of highly potent 5-HT3 receptor ligands. J Med Chem. 55: 8603-8614.
  27. Akdemir, A., E. Edink, A.J. Thompson, S.C.R. Lummis, A.J. Kooistra, C. de Graaf and I.J.P. de Esch. 2012. Identification of novel α7 nicotinic receptor ligands by in silico screening against the crystal structure of a chimeric α7 receptor ligand binding domain. Bioorg Med Chem. 20: 5992-6002.
  28. Huang, S.H., T.G. Lewis, S.C. Lummis, A.J.Thompson, M. Chebeb, G.A. Johnston and R.K. Duke. 2012. Mixed antagonistic effects of the ginkgolides at recombinant human rho1 GABA C receptors. Neuropharmacology. 63: 1127-1139.
  29. Thompson, A.J., M. Alqazzaz, C. Ulens and S.C.R. Lummis. 2012. The pharmacological profile of ELIC, a prokaryotic GABA-gated receptor. Neuropharmacology. 63; 761-767.
  30. Utkin, Y. N., C. Weise, I.E. Kashererov, T.V. Andreeva, E.V. Kryokova, M.N. Zhmak, V.G. Starkov, H.N Anh, D. Bertrand, J. Ramerstorfer, W. Sieghart, A.J. Thompson, S.C.R. Lummis and V.I. Tsetlin. 2012. Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor. J Biol Chem. 287; 27079-27086.
  31. Thompson, A.J., I. McGonigle, R. Duke, G. A. Johnston and S.C.R. Lummis. 2012. A single amino acid determines the toxicity of Ginkgo biloba extracts. FASEB J. 26: 1884-1891.
  32. Thompson, A.J., M.H.P. Verheij, I.J.P. De Esch and S.C.R. Lummis. 2012. VUF10166, a Novel Compound with Differing Activities at 5-HT 3A and 5-HT3AB Receptors. JPET. 341: 350-359.
  33. Simonin, J., S.K.V. Vernekar, A.J. Thompson, S.C.R. Lummis, D. Hothersall, C. Connolly and M. Lochner. 2012. High-affinity Fluorescent Ligands for the 5-HT3 Receptor. Bioorg. Med. Chem. Lett. 22: 1151-1155.
  34. Alqazzaz, M., A.J. Thompson, K.L. Price., HG. Bretinger and S.C.R. Lummis. 2011. Cys-loop Receptor Channel Blockers also Block GLIC. Biophys. J. 101: 1-7.
  35. Thompson, A.J., K.L. Price and S.C.R. Lummis. 2011. Cysteine Modification Reveals Which Subunits Form the Ligand Binding Site in Human Heteromeric 5-HT3AB Receptors. J. Physiol. 589: 4243-4257.
  36. Lummis, S.C.R., A.J. Thompson, M. Bencherif and H.A. Lester. 2011. Varenicline is a Potent Agonist of the Human 5-HT3 Receptor. JPET. 339: 125-131.
  37. Verheij, M.H.P., C. de Graaf, G.E. de Kloe, S. Nijmeijer, H.F. Vischer, R.A. Smits, O.P. Zuiderveld, S. Hulscher, L. Silvestri, A.J. Thompson, J.E. van Muijlwijk-Koezen, S.C.R. Lummis, R. Leurs and I.J.P. de Esch. 2011. Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H4 and the ion channel serotonin 5-HT3AB Receptors. Bioorg Med Chem Lett. 21: 5460-5464.
  38. Thompson, A.J., R.K. Duke and S.C.R. Lummis. 2011. Binding Sites for Bilobalide, Diltiazem, Ginkgolide and Picrotoxinin at the 5-HT 3 Receptor. Mol. Pharmacol. 80: 183-190.
  39. Wheeler, D.W., A.J. Thompson, F. Corletto, J. Reckless, J.C.T. Loke, N. Lapaque, A.J. Grant, P. Mastroeni, D.J. Grainger, C.L. Padgett, J.A. O?Brien, N.G.A. Miller, J. Trowsdale, S.C.R. Lummis, D.K. Menon and J.S. Beech. 2011. Anaesthetic Impairment of Immune Function is Mediated Via GABAA Receptors. PLoS One. 6: e17152.
  40. Thompson, A.J., G.E. Jarvis, R.K. Duke, G.A.R. Johnston and S.C.R. Lummis. 2011. Ginkgolide B and Bilobalide Block the Pore of the 5-HT3 Receptor at a Location that Overlaps the Picrotoxin Binding Site. Neuropharmacology. 60: 488-495.
  41. Thompson, A.J., H.A. Lester and S.C.R. Lummis. 2010. The Structural Basis of Cys-loop Receptor Function. Quart. Rev. Biophys. 43: 449-499.
  42. Thompson, A.J., M.H.P. Verheij, R. Leurs, I.J.P. De Esch and S.C.R. Lummis. 2010. An Efficient and Information Rich Biochemical Method Design for Fragment Library Screening on Ion Channels. BioTechniques. 49: 822-829.
  43. Quek, G.X.J., D. Lin, J.I. Halliday, N. Absalom, J.I. Ambrus, A.J. Thompson, M. Lochner, S.C.R. Lummis, M.D. McLeod and M. Chebib. 2010. Identifying the Binding Site of Novel Methyllycaconitine (MLA) Analogs at alpha4beta2 Nicotinic Acetylcholine Receptors. ACS Chem Neurosci. 1: 796-809.
  44. Vernekar, S.K., H.S. Hallaq, G.C. Clarkson, A.J. Thompson, L. Silvestri, S.C.R. Lummis and M. Lochner. 2010. Towards Biophysical Probes for the 5-HT3 Receptor: Structure-Activity Relationship Study of Granisetron Derivatives. J Med Chem. 53:2324-2328.
  45. Thompson, A.J., P.K. Mander and G.C. Brown. 2009. The NO donor DETA-NONOate reversibly activates an inward current in neurons that is not mediated by nitric oxide Br J Pharmacol. 158:1338-1343.
  46. Thompson, A.J. and S.C. Lummis. 2009. Calcium modulation of 5-HT3 receptor binding and function. Neuropharmacology. 56:285-291.
  47. Thompson, A.J. and S.C.R. Lummis. 2008. Antimalarial Drugs Inhibit Human 5-HT3 and GABAA, but not GABAC Receptors. Br J Pharmacol. 153:1686-1696.
  48. Thompson, A.J., M. Lochner, and S.C.R. Lummis. 2008. Loop B is a Major Structural Component of the 5-HT3 Receptor. Biophys. J. 95:5728-5736.
  49. Price, K.L. , K.S. Bower, A.J. Thompson, H.A. Lester, D.A. Dougherty, and S.C. Lummis. 2008. A hydrogen bond in loop A is critical for the binding and function of the 5-HT3 receptor. Biochemistry. 47:6370-6377.
  50. Thompson, A.J. and S.C.R. Lummis. 2007. The 5-HT3 Receptor as a Therapeutic Target. Expert Opinions on Therapeutic Targets. 11:527-540.
  51. Thompson, A.J., M. Lochner, and S.C. Lummis. 2007. The antimalarial drugs quinine, chloroquine and mefloquine are antagonists at 5-HT3 receptors. Br J Pharmacol. 151:666-677.
  52. Thompson, A.J., N.L. Sullivan, and S.C.R. Lummis. 2006. Characterisation of 5-HT3 receptor mutations identified in schizophrenic patients and expressed in HEK293 cells. J. Mol. Neurosci. 30:273-281.
  53. Thompson, A.J., L. Zhang, and S.C.R. Lummis. 2006. The 5-HT3 Receptor. In. The serotonin receptors: from molecular pharmacology to human therapeutics. (Ed. B.L. Roth). Humana Press, New Jersey, USA:439-457.
  54. Thompson, A.J., and S.C.R. Lummis. 2006. The Relationship Between Structure and Function in the 5-HT3 Receptor: The Transmembrane Domain. In. Biological and Biophysical Aspects of Ligand-Gated Ion Channel Receptor Superfamilies. (Ed. H.R. Arias). Research Signpost, Kerala, India: 155-170.
  55. Thompson, A.J., C.L. Padgett, and S.C. Lummis. 2006. Mutagenesis and molecular modeling reveal the importance of the 5-HT3 receptor F-loop. J Biol Chem. 281:16576-16582.
  56. Thompson, A.J., P.L. Chau, S.L. Chan, and S.C. Lummis. 2006. Unbinding pathways of an agonist and an antagonist from the 5-HT3 receptor. Biophys J. 90:1979-1991.
  57. Thompson, A.J. and S.C. Lummis. 2006. 5-HT3 receptors. Curr Pharm Des. 12:3615-3630.
  58. Sullivan, N.L., A.J. Thompson, K. Price, and S.C.R. Lummis. 2006. Defining the roles of Asn-128, Glu-129 and Phe-130 in loop A of the 5-HT3 receptor. Mol Mem Biol. 23:1-10.
  59. Thompson, A.J., K.L. Price, D.C. Reeves, S.L. Chan, P.L. Chau, and S.C. Lummis. 2005. Locating an antagonist in the 5-HT3 receptor binding site using modeling and radioligand binding. J Biol Chem. 280:20476-20482.
  60. Thompson, A.J. and S.C. Lummis. 2003. A single ring of charged amino acids at one end of the pore can control ion selectivity in the 5-HT3 receptor. Br J Pharmacol. 140:359-365.
  61. Hubbard, P.C., A.J. Thompson, and S.C. Lummis. 2000. Functional differences between splice variants of the murine 5-HT3A receptor: possible role for phosphorylation. Mol Brain Res. 81:101-108.
  62. Duce, I.R., T.R. Khan, A.C. Green, A.J. Thompson, S.P.M. Warburton, and J.T. Wong. 1999. Calcium Channels in Insects. In. Progress in Neuropharmacology and Neurotoxicology of Pesticides and Drugs. (Ed: D.J. Beadle). Royal Soc. Chem. Cambridge: 56-66.
  63. Schuler, T.H., D. Martinez-Torres, A.J. Thompson, I. Denholm, A.L. Devonshire, I.R. Duce, and M.S. Williamson. 1998. Toxicological, Electrophysiological, and Molecular Characterisation of Knockdown Resistance to Pyrethroid Insecticides in the Diamondback Moth, Plutella xylostella (L.). Pest. Biochem. Physiol. 59:169-182.
  64. Schuler, T.H., D. Martinez-Torres, A.J. Thompson, I. Denholm, A.L. Devonshire, I.R. Duce, and M.S. Williamson. (1996). Characterisation of knockdown resistance to pyrethroid insecticides in Plutella xylostella. In. The Management of Diamondback Moth and Other Crucifer Pests. Proc. 3rd Int. Workshop, Kuala Lumpur, Malaysia, 29 Oct.-1 Nov., 1996. (Eds: A. Sivapragasam, W.H. Loke, A.K. Hussan and G.S. Lim): 215-218.